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Martinez et al(2003) Lactobacillus casei Shirota prevention approach for healthy children with mild acute infection treated with antibiotics

Martinez et al(2003) Lactobacillus casei Shirota prevention approach for healthy children with mild acute infection treated with antibiotics

Citation

Martinez CO, Paz VS, O’Donnell A (2003) Lactobacillus casei Shirota prevention approach for healthy children with mild acute infection treated with antibiotics. Pediatric Research 4(2)S:174A-174A

Objective

To assess the efficacy of Lactobacillus casei Shirota (LcS) in preventing acute diarrhoea in healthy children on antibiotic therapy for a mild infection

Methods

In a randomised clinical trial, 88 healthy children (between 12-144 months old) consumed either the probiotic LcS or a placebo daily until the cessation of antibiotic treatment. Follow-up assessments occurred through the outpatient clinic.

Results

A significantly lower incidence of diarrhoea was seen in the probiotic group compared with the control group (P = 0.01).

Conclusions

Probiotic consumption was associated with a significantly lower incidence of acute diarrhoea in healthy children on antibiotic therapy for a mild infection.

 
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