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Tilley L et al (2014) A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools

Tilley L et al (2014) A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools

Citation

Tilley L, Keppens K, Kushiro A, Takada T, Sakai T, Vaneechoutte M, Degeest B (2014) A probiotic fermented milk drink containing Lactobacillus casei strain Shirota improves stool consistency of subjects with hard stools. International Journal of Probiotics & Prebiotics 9(1/2):23-30.

Objective

To investigate earlier observations that ingestion of Lactobacillus casei Shirota (LcS) is associated with improved bowel habit, including improved stool consistency

Methods

Double-blind, placebo-controlled, randomised trial involving 120 adult patients from Belgian GP surgeries, who were suffering from mild constipation. This was defined as four or less bowel movements per week, and hard or lumpy stools in at least 25% of times when stools were passed. 

The four-week intervention was with one bottle a day of LcS-fermented probiotic drink or placebo. Faecal samples from half the subjects were analysed after the two-week run-in period, post-intervention, and after the two-week follow-up. Stool consistency was analysed using a patient questionnaire based on the Bristol Stool Scale.

Results

Compared to the placebo group, the subjects taking the LcS-probiotic drink experienced a significant improvement in stool consistency; the stools became softer. This was associated with detection of viable LcS in the stools.  Both groups showed improved defaecation frequency.

Conclusions

For people passing hard stools, ingestion of the probiotic fermented milk drink containing LcS was associated with significantly improvement of stool consistency, with their stools becoming softer (compared to the placebo group). This may well be due to a change in the intestinal microbiota.

 
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